I pick my seats for a reason, but as long as I’m not being inconvenienced too much by the request, and the request is a reasonable one, I try to be accommodating. Sometimes I get a thank you.
So it was actually thrilling to hear about a woman that tried hard to really show her appreciate for a passenger that agreed to switch seats. She kept trying to offer $100 as a thank you on a Boston – Atlanta flight in first class.