I’ve always found US government travel warnings to be overly cautious. I have no problem transiting the Istanbul airport, booking an award on Turkish Airlines (just hope your seat opponent doesn’t whisper to a flight attendant that you’re a Gulenist).
Since I’m willing to go places like this, it seems worth highlighting a counterpoint. The government doesn’t say ‘don’t go to Mexico’ just that there are some Bad Hombres™ there.